The impact of anxiety on vulvar dermatological diseases: a systematic review.
Vulvar inflammatory dermatoses, including lichen sclerosus, lichen planus, lichen simplex chronicus, and psoriasis, have been shown to impact mental health and quality of life. We aimed to synthesize and evaluate the current literature regarding the association between anxiety and vulvar inflammator…
Patients' acceptance of televulvology and preferences for vulvar lichen sclerosus follow-up appointments: a questionnaire cohort study.
To explore motivations and barriers of Dutch vulvar Lichen sclerosus (LS) patients for accepting televulvology and patients' preferences for follow-up visits. Cohort questionnaire pilot study. Outpatient clinic of a large teaching hospital. 89 patients with vulvar LS in follow-up during February and…
Integrating multi-omics and mendelian randomization identifies therapeutic targets for Lichen Sclerosus: A druggable genome-wide study.
Lichen sclerosus (LS) is a chronic inflammatory skin disease characterized by limited treatment options and an unclear pathogenesis. This study aimed to identify potential therapeutic targets for LS by integrating druggable genome (DG) data with multi-omics and Mendelian randomization (MR). Blood ex…
Immunological aspects and quality of life among patients with lichen sclerosus.
Lichen sclerosus (LS) is a chronic, inflammatory dermatosis that predominantly affects the anogenital region. The ethology of LS is currently regarded as multifactorial, encompassing genetic, autoimmune and tissue remodelling factors, as well as oxidative stress or urine occlusion. Clinical manifest…
Lysis of Vulvar Adhesions and Sexual Function in Vulvar Lichen Sclerosus.
To evaluate the effects of surgical interventions, specifically surgical correction of introital stenosis and clitoral phimosis in a procedure called lysis of vulvar adhesions, on sexual function, sexual distress, and overall patient satisfaction in individuals with vulvar lichen sclerosus. A pre-po…