Narcolepsy

204 papers

A chronic neurological disorder causing excessive daytime sleepiness, sudden muscle weakness, and sleep disruption.

Excessive sleepinessCataplexySleep paralysisHallucinationsDisrupted night sleepBrain fog

Research

204
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PubMed

Clinical insights into catathrenia: A real-world analysis from a tertiary sleep center.

Catathrenia is a rare sleep-related breathing disorder marked by groaning during prolonged expiration, often underrecognized or misdiagnosed as obstructive or central sleep apnoea (OSA or CSA) or parasomnia. Understanding its clinical and polysomnographic features is essential for accurate diagnosis…

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The impact of insomnia and excessive daytime sleepiness on depression and suicidal ideation in adolescents: A three-year longitudinal study.

Insomnia and excessive daytime sleepiness (EDS) were associated with adverse mental health outcomes in adolescents, but their combined effects remained unclear. This study examined the associations between insomnia and EDS with mental health outcomes over a 3-year follow-up period. This study was a…

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PubMed

Narcolepsy type 1: an environment-influenced disease.

Narcolepsy type 1 (NT1) is a chronic and non-progressive neurological disorder that frequently arises in childhood. NT1 is characterized by loss of physiological boundaries between wakefulness and sleep, excessive daytime sleepiness, cataplexy, sleep paralysis, and hypnagogic or hypnopompic hallucin…

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PubMed

The use of oxybates in patients with comorbid narcolepsy and mental health disorders.

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Sleep disturbances in patients with vasculitis.

Research on sleep patterns in individuals with vasculitis remains limited. This SleepVasc study aimed to 1) evaluate sleep disturbances and a range of sleep health dimensions in individuals with vasculitis, and 2) identify potential risk factors for sleep problems/disturbances/disorders. SleepVasc w…

narcolepsyvasculitis
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PubMed

Sleep and Substance Use Disorders: A Primer for the Clinician.

The neurophysiology of sleep and the pathophysiology of substance use disorders (SUDs) involve overlaps in neurotransmitters and pathways. SUDs and substance withdrawal are accompanied by significant impairments in sleep. Conversely, sleep disturbances are known to predispose for SUDs. Sleep disorde…

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PubMed

Sodium-relevant comorbidity risk factors are highly prevalent in individuals with narcolepsy or idiopathic hypersomnia.

Individuals with narcolepsy or idiopathic hypersomnia (IH) present with a high comorbidity burden that may confer elevated risk for negative clinical outcomes associated with excess sodium intake. This study characterized the prevalence and profiles of sodium-relevant comorbidity risk factors among…

narcolepsyidiopathic hypersomnia
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PubMed

Assessment of readiness in the diagnosis and management of central disorders of hypersomnolence: A survey of sleep medicine program directors and fellowship graduates.

Central disorders of hypersomnolence (CDH), including narcolepsy, idiopathic hypersomnia, and recurrent hypersomnia, are rare conditions that pose challenges in sleep medicine fellowship training. Limited exposure to these disorders, variability in training experiences, and growing complexity of dia…

narcolepsyidiopathic hypersomnia
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