Ramadan fasting in patients with primary adrenal insufficiency: evaluation of the risk of complications, quality of life and sleep, and associated factors.
The study aimed to evaluate the risk of complications, quality of life (QoL) and quality of sleep (QoS) during Ramadan fasting (RF) in patients with primary adrenal insufficiency (PAI) and determine the associated factors. It was an interventional, randomised, crossover, self-controlled study, inclu…
Letter to the Editor from Erdoğan Özbuğday and Karakurt: "Primary adrenal insufficiency resulting in diagnosis of rare ABCD1 pathogenic variant in X-linked adrenoleukodystrophy".
Chronic Central Adrenal Insufficiency in a Patient With Remote Traumatic Brain Injury and an Apparently Adequate Standard-Dose ACTH Response: A Case Report.
In patients with a remote history of traumatic brain injury, central adrenal insufficiency may remain unrecognized for decades. An apparently adequate response to standard-dose ACTH stimulation should not preclude further evaluation of the hypothalamic-pituitary-adrenal axis when clinical and bioche…
Autoimmune adrenalitis in adolescents in Germany: a series of 4 cases.
This case report summarises clinical findings in four adolescents (aged 14-17 years) diagnosed with autoimmune adrenalitis at a German University Children's Hospital between 2019 and 2025. Clinical presentation varied and included fatigue, arterial hypotension, depressive symptoms, hyperpigment…
Perioperative adrenal insufficiency presenting as refractory hypotension: A CARE-compliant article.
Adrenal insufficiency (AI) is a rare but potentially life-threatening cause of perioperative hemodynamic instability characterized by an inadequate cortisol response to physiological stress. We report a case of a 77-year-old woman undergoing oblique lumbar interbody fusion who developed profound int…
A Multidisciplinary Approach to the Anesthetic Management of Patients With Duchenne Muscular Dystrophy.
Duchenne muscular dystrophy (DMD) is an inherited neuromuscular disorder with multisystem involvement that causes progressive muscular weakness and cardiorespiratory dysfunction. The first comprehensive recommendations regarding anesthetic management are now almost 20 years old and, in the interval,…
Functional analysis of adrenocorticotropic-hormone-producing pituitary cells derived from human pluripotent stem cells in murine and primate models of hypopituitarism.
Hypopituitarism has a prevalence of approximately 45.5 cases per 100,000 population, is therefore not a rare condition. Hypopituitarism does not resolve spontaneously and is designated as an intractable disease. In particular, deficiency of adrenocorticotropic hormone (ACTH) can result in adrenal in…
Metastatic large cell neuroendocrine carcinoma: a rare cause of hypopituitarism.
Pituitary metastases from pulmonary large cell neuroendocrine carcinoma (LCNEC) are exceedingly rare but should be considered in patients presenting with arginine vasopressin deficiency and panhypopituitarism in the context of known or suspected metastatic lung cancer. Early recognition and prompt i…