Crohn's Disease

Wearable Technology and Remote Physiological Monitoring in Inflammatory Bowel Disease: Erratum.

Granulomatous inflammation in histopathological samples: examining the aetiological spectrum, diagnostic challenges, and future perspectives.

Granulomas can be found in different tissues and are associated with a variety of processes. To understand the primary diagnoses is the aim of this study. We retrospectively described a cohort of patients with a diagnosis of granulomas in histopathological samples over an 11-year period. Demographic…

Towards standardized gut microbiota diagnostics: normobiosis beyond geographical borders.

Defining clinically meaningful reference states of the human gut microbiota remains a major barrier to the clinical translation of microbiome testing, largely due to variability across populations. We aimed at evaluating whether dysbiosis can be identified in a standardized, geography-independent ma…

Unraveling the Clinical Puzzle of Cerebral Venous Sinus Thrombosis in Ulcerative Colitis: Insights from a Systematic Review.

Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) that primarily affects the colon. Among its extraintestinal complications, cerebral venous sinus thrombosis (CVST) is a rare yet potentially life-threatening emergency that can manifest as headaches, seizures, and/or neurological…

The Roles of Complementary Structured Exercise and Physical Therapy in The Aging and Older Adult IBD Patient Care Team.

Structured exercise (SE) and physical therapy (PT) are integral components of disease management. Older adults with inflammatory bowel disease (IBD) represent a growing proportion of patients, and are at disproportionate risk of functional decline due to the combined effects of aging, chronic inflam…

PSC-DM: A Validated Clinical Diagnostic Model for Distinguishing Primary From Secondary Sclerosing Cholangitis.

Primary sclerosing cholangitis (PSC) is a rare, progressive cholangiopathy for which diagnosis remains challenging because of the absence of disease-specific markers and the presence of secondary causes of sclerosing cholangitis (SSC) that closely mimic its clinical presentation. Diagnostic uncertai…

Imaging Updates in Inflammatory Bowel Disease.

Magnetic resonance enterography (MRE) is a key noninvasive imaging modality for the diagnosis and longitudinal assessment of inflammatory bowel disease (IBD), particularly Crohn's disease. The global burden of IBD is increasing, with millions affected in North America and Europe and rapidly rising i…

PET/MR Imaging of the Gastrointestinal Tract.

PET/MR imaging combines molecular PET data with multiparametric MR imaging in a single reduced-radiation examination of the gastrointestinal tract. For oncologic indications, the hybrid modality adds value in hepatic metastasis detection, locoregional staging, and posttreatment response assessment.…