Cytotoxic Lesion of the Corpus Callosum After Hospital-Administered Intravenous Fentanyl for Trigeminal Neuralgia: A Case Report and Focused Review.
Fentanyl-associated neurotoxicity is increasingly recognized across illicit, inhalational, transdermal, pediatric, and delayed posthypoxic exposures, but isolated splenial CLOCC after hospital-administered intravenous fentanyl has not been well characterized. This is a single-patient case report wit…
Letter to the Editors on "Analysis of the effects of combined electrical spinal cord stimulation and pregabalin therapy in patients with herpes zoster trigeminal neuralgia" by Jiang et al.
A meta-analysis of pain intensity changes after placebo interventions in facial pain.
Interpreting pain improvements after interventions in clinical settings is challenging because placebo effects can influence patient-reported outcomes. In clinical practice, pain intensity reductions of 30% or greater are commonly considered indicative of meaningful analgesic benefit. However, the l…
The Interrelationship Between Trigeminal Neuralgia and Dental Conditions: A Systematic Review of Diagnostic Pitfalls and Clinical Implications.
Trigeminal neuralgia (TN) is a severe neuropathic pain disorder frequently misdiagnosed as odontogenic pain, often leading to unnecessary dental procedures and delayed neurological diagnosis. A systematic review was conducted in PubMed, Scopus, Web of Science, and CINAHL for English-language studies…
Division Specific Biologically Effective Dose Predicts Gamma Knife Radiosurgery Outcomes in Multiple Sclerosis-Associated Trigeminal Neuralgia.
Outcomes after Gamma Knife surgery (GKS) for multiple sclerosis-related trigeminal neuralgia type 1 (MS-TN1) remain variable, and the role of biologically effective dose (BED) distribution across trigeminal nerve subregions is not well defined. This study evaluated whether BED-based volumetric param…
Assessment of the accuracy and feasibility of CT fusion with real-time US guidance for percutaneous radiofrequency trigeminal rhizotomy.
To quantitatively assess the spatial accuracy and technical feasibility of computed tomography (CT) fusion with real-time ultrasound (US) guidance (CTF-USG) for percutaneous radiofrequency trigeminal rhizotomy (PRF-TR) in patients with trigeminal neuralgia (TN). This prospective observational study…
Thermosensitive hydroxypropyl chitin-based hydrogel for trigeminal neuralgia: Rapid analgesia, myelin repair, and attenuation of gamma-band hyperactivity in the spinal trigeminal nucleus caudalis.
Trigeminal neuralgia is a debilitating neuropathic disorder characterized by the complex interplay of peripheral demyelination and central sensitization. Current pharmacotherapies remain palliative, limited by systemic toxicity and an inability to reverse pathological microenvironments. Herein, an i…
Percutaneous balloon compression followed by perineural methylprednisolone for trigeminal neuralgia: A 50-patient retrospective series with 12-month outcomes.
To describe pain outcomes and safety after a combined protocol of percutaneous balloon compression (PBC) followed immediately by perineural methylprednisolone in adults with pharmacoresistant trigeminal neuralgia. We conducted a multicentre, single-arm, retrospective observational series without a c…